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Development and Application of Human Renal Proximal Tubule Epithelial Cells for Assessment of Compound Toxicity

Kidney toxicity is a major problem both in drug development and clinical settings. It is difficult to predict nephrotoxicity in part because of the lack of appropriate in vitro cell models, limited endpoints, and the observation that the activity of membrane transporters which plays important roles...

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Bibliografski detalji
Izdano u:Curr Chem Genom Transl Med
Glavni autori: Li, Shuaizhang, Zhao, Jinghua, Huang, Ruili, Steiner, Toni, Bourner, Maureen, Mitchell, Michael, Thompson, David C., Zhao, Bin, Xia, Menghang
Format: Artigo
Jezik:Inglês
Izdano: Bentham Open 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362976/
https://ncbi.nlm.nih.gov/pubmed/28401035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/2213988501711010019
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