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Development and Application of Human Renal Proximal Tubule Epithelial Cells for Assessment of Compound Toxicity
Kidney toxicity is a major problem both in drug development and clinical settings. It is difficult to predict nephrotoxicity in part because of the lack of appropriate in vitro cell models, limited endpoints, and the observation that the activity of membrane transporters which plays important roles...
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| Veröffentlicht in: | Curr Chem Genom Transl Med |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Bentham Open
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5362976/ https://ncbi.nlm.nih.gov/pubmed/28401035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/2213988501711010019 |
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