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Chaperones in Polyglutamine Aggregation: Beyond the Q-Stretch
Expanded polyglutamine (polyQ) stretches in at least nine unrelated proteins lead to inherited neuronal dysfunction and degeneration. The expansion size in all diseases correlates with age at onset (AO) of disease and with polyQ protein aggregation, indicating that the expanded polyQ stretch is the...
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| Pubblicato in: | Front Neurosci |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5362620/ https://ncbi.nlm.nih.gov/pubmed/28386214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00145 |
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