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CCN2 reduction mediates protective effects of BMP7 treatment in obstructive nephropathy

Treatment with rhBMP7 exerts profound protective effects in a wide variety of experimental models of renal disease. However, little is known about how these protective effects are mediated, and which cells in the kidney are targeted by exogenous rhBMP7 treatment. To determine if rhBMP7 increases glo...

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Detalhes bibliográficos
Publicado no:J Cell Commun Signal
Main Authors: Falke, Lucas L., Leeuwis, Jan Willem, Lyons, Karen M., Mummery, Christine L., Nguyen, Tri Q., Goldschmeding, Roel
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362571/
https://ncbi.nlm.nih.gov/pubmed/27766493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-016-0358-2
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