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CCN2 reduction mediates protective effects of BMP7 treatment in obstructive nephropathy

Treatment with rhBMP7 exerts profound protective effects in a wide variety of experimental models of renal disease. However, little is known about how these protective effects are mediated, and which cells in the kidney are targeted by exogenous rhBMP7 treatment. To determine if rhBMP7 increases glo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Commun Signal
Hauptverfasser: Falke, Lucas L., Leeuwis, Jan Willem, Lyons, Karen M., Mummery, Christine L., Nguyen, Tri Q., Goldschmeding, Roel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362571/
https://ncbi.nlm.nih.gov/pubmed/27766493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-016-0358-2
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