CTGF Inhibits BMP-7 Signaling in Diabetic Nephropathy

In diabetic nephropathy, connective tissue growth factor (CTGF) is upregulated and bone morphogenetic protein 7 (BMP-7) is downregulated. CTGF is known to inhibit BMP-4, but similar cross-talk between BMP-7 and CTGF has not been studied. In this study, it was hypothesized that CTGF acts as an inhibi...

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Autores principales: Nguyen, Tri Q., Roestenberg, Peggy, van Nieuwenhoven, Frans A., Bovenschen, Niels, Li, Zeke, Xu, Leon, Oliver, Noelynn, Aten, Jan, Joles, Jaap A., Vial, Cecilia, Brandan, Enrique, Lyons, Karen M., Goldschmeding, Roel
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Nephrology 2008
Materias:
Basic Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573007/
https://ncbi.nlm.nih.gov/pubmed/18632843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007111261
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