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CTGF Inhibits BMP-7 Signaling in Diabetic Nephropathy

In diabetic nephropathy, connective tissue growth factor (CTGF) is upregulated and bone morphogenetic protein 7 (BMP-7) is downregulated. CTGF is known to inhibit BMP-4, but similar cross-talk between BMP-7 and CTGF has not been studied. In this study, it was hypothesized that CTGF acts as an inhibi...

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Detalhes bibliográficos
Main Authors: Nguyen, Tri Q., Roestenberg, Peggy, van Nieuwenhoven, Frans A., Bovenschen, Niels, Li, Zeke, Xu, Leon, Oliver, Noelynn, Aten, Jan, Joles, Jaap A., Vial, Cecilia, Brandan, Enrique, Lyons, Karen M., Goldschmeding, Roel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573007/
https://ncbi.nlm.nih.gov/pubmed/18632843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007111261
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