The Angio-Fibrotic Switch of VEGF and CTGF in Proliferative Diabetic Retinopathy

BACKGROUND: In proliferative diabetic retinopathy (PDR), vascular endothelial growth factor (VEGF) and connective tissue growth factor (CTGF) cause blindness by neovascularization and subsequent fibrosis, but their relative contribution to both processes is unknown. We hypothesize that the balance b...

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Hlavní autoři: Kuiper, Esther J., Van Nieuwenhoven, Frans A., de Smet, Marc D., van Meurs, Jan C., Tanck, Michael W., Oliver, Noelynn, Klaassen, Ingeborg, Van Noorden, Cornelis J. F., Goldschmeding, Roel, Schlingemann, Reinier O.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443281/
https://ncbi.nlm.nih.gov/pubmed/18628999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002675
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