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The Angio-Fibrotic Switch of VEGF and CTGF in Proliferative Diabetic Retinopathy

BACKGROUND: In proliferative diabetic retinopathy (PDR), vascular endothelial growth factor (VEGF) and connective tissue growth factor (CTGF) cause blindness by neovascularization and subsequent fibrosis, but their relative contribution to both processes is unknown. We hypothesize that the balance b...

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Autors principals: Kuiper, Esther J., Van Nieuwenhoven, Frans A., de Smet, Marc D., van Meurs, Jan C., Tanck, Michael W., Oliver, Noelynn, Klaassen, Ingeborg, Van Noorden, Cornelis J. F., Goldschmeding, Roel, Schlingemann, Reinier O.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443281/
https://ncbi.nlm.nih.gov/pubmed/18628999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002675
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