A shift in the balance of vascular endothelial growth factor and connective tissue growth factor by bevacizumab causes the angiofibrotic switch in proliferative diabetic retinopathy

INTRODUCTION: In proliferative diabetic retinopathy (PDR), vascular endothelial growth factor (VEGF) and connective tissue growth factor (CTGF) may cause blindness by neovascularisation followed by fibrosis of the retina. It has previously been shown that a shift in the balance between levels of CTG...

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Detalhes bibliográficos
Main Authors: Van Geest, Rob J, Lesnik-Oberstein, Sarit Y, Tan, H Stevie, Mura, Marco, Goldschmeding, Roel, Van Noorden, Cornelis J F, Klaassen, Ingeborg, Schlingemann, Reinier O
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2012
Assuntos:
Laboratory Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308470/
https://ncbi.nlm.nih.gov/pubmed/22289291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bjophthalmol-2011-301005
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