A shift in the balance of vascular endothelial growth factor and connective tissue growth factor by bevacizumab causes the angiofibrotic switch in proliferative diabetic retinopathy

INTRODUCTION: In proliferative diabetic retinopathy (PDR), vascular endothelial growth factor (VEGF) and connective tissue growth factor (CTGF) may cause blindness by neovascularisation followed by fibrosis of the retina. It has previously been shown that a shift in the balance between levels of CTG...

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Bibliografiset tiedot
Päätekijät: Van Geest, Rob J, Lesnik-Oberstein, Sarit Y, Tan, H Stevie, Mura, Marco, Goldschmeding, Roel, Van Noorden, Cornelis J F, Klaassen, Ingeborg, Schlingemann, Reinier O
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMJ Group 2012
Aiheet:
Laboratory Science
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308470/
https://ncbi.nlm.nih.gov/pubmed/22289291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bjophthalmol-2011-301005
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