A shift in the balance of vascular endothelial growth factor and connective tissue growth factor by bevacizumab causes the angiofibrotic switch in proliferative diabetic retinopathy

INTRODUCTION: In proliferative diabetic retinopathy (PDR), vascular endothelial growth factor (VEGF) and connective tissue growth factor (CTGF) may cause blindness by neovascularisation followed by fibrosis of the retina. It has previously been shown that a shift in the balance between levels of CTG...

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Hlavní autoři: Van Geest, Rob J, Lesnik-Oberstein, Sarit Y, Tan, H Stevie, Mura, Marco, Goldschmeding, Roel, Van Noorden, Cornelis J F, Klaassen, Ingeborg, Schlingemann, Reinier O
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Group 2012
Témata:
Laboratory Science
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308470/
https://ncbi.nlm.nih.gov/pubmed/22289291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bjophthalmol-2011-301005
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