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Connective Tissue Growth Factor Is Necessary for Retinal Capillary Basal Lamina Thickening in Diabetic Mice

Experimental prevention of basal lamina (BL) thickening of retinal capillaries ameliorates early vascular changes caused by diabetes. Connective tissue growth factor (CTGF) is upregulated early in diabetes in the human retina and is a potent inducer of expression of BL components. We hypothesize tha...

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Bibliografiske detaljer
Main Authors: Kuiper, Esther J., van Zijderveld, Rogier, Roestenberg, Peggy, Lyons, Karen M., Goldschmeding, Roel, Klaassen, Ingeborg, Van Noorden, Cornelis J.F., Schlingemann, Reinier O.
Format: Artigo
Sprog:Inglês
Udgivet: Histochemical Society 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443606/
https://ncbi.nlm.nih.gov/pubmed/18474939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/jhc.2008.950980
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