Connective Tissue Growth Factor Is Necessary for Retinal Capillary Basal Lamina Thickening in Diabetic Mice

Experimental prevention of basal lamina (BL) thickening of retinal capillaries ameliorates early vascular changes caused by diabetes. Connective tissue growth factor (CTGF) is upregulated early in diabetes in the human retina and is a potent inducer of expression of BL components. We hypothesize tha...

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Auteurs principaux: Kuiper, Esther J., van Zijderveld, Rogier, Roestenberg, Peggy, Lyons, Karen M., Goldschmeding, Roel, Klaassen, Ingeborg, Van Noorden, Cornelis J.F., Schlingemann, Reinier O.
Format: Artigo
Langue:Inglês
Publié: Histochemical Society 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443606/
https://ncbi.nlm.nih.gov/pubmed/18474939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/jhc.2008.950980
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