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The role of plasmalemma vesicle-associated protein in pathological breakdown of blood–brain and blood–retinal barriers: potential novel therapeutic target for cerebral edema and diabetic macular edema

Breakdown of the blood–brain barrier (BBB) or inner blood–retinal barrier (BRB), induced by pathologically elevated levels of vascular endothelial growth factor (VEGF) or other mediators, can lead to vasogenic edema and significant clinical problems such as neuronal morbidity and mortality, or visio...

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Detalhes bibliográficos
Publicado no:Fluids Barriers CNS
Main Authors: Bosma, Esmeralda K., van Noorden, Cornelis J. F., Schlingemann, Reinier O., Klaassen, Ingeborg
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146740/
https://ncbi.nlm.nih.gov/pubmed/30231925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-018-0109-2
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