The role of plasmalemma vesicle-associated protein in pathological breakdown of blood–brain and blood–retinal barriers: potential novel therapeutic target for cerebral edema and diabetic macular edema

Breakdown of the blood–brain barrier (BBB) or inner blood–retinal barrier (BRB), induced by pathologically elevated levels of vascular endothelial growth factor (VEGF) or other mediators, can lead to vasogenic edema and significant clinical problems such as neuronal morbidity and mortality, or visio...

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Vydáno v:Fluids Barriers CNS
Hlavní autoři: Bosma, Esmeralda K., van Noorden, Cornelis J. F., Schlingemann, Reinier O., Klaassen, Ingeborg
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6146740/
https://ncbi.nlm.nih.gov/pubmed/30231925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-018-0109-2
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