CTGF Inhibits BMP-7 Signaling in Diabetic Nephropathy

In diabetic nephropathy, connective tissue growth factor (CTGF) is upregulated and bone morphogenetic protein 7 (BMP-7) is downregulated. CTGF is known to inhibit BMP-4, but similar cross-talk between BMP-7 and CTGF has not been studied. In this study, it was hypothesized that CTGF acts as an inhibi...

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Bibliografiske detaljer
Main Authors: Nguyen, Tri Q., Roestenberg, Peggy, van Nieuwenhoven, Frans A., Bovenschen, Niels, Li, Zeke, Xu, Leon, Oliver, Noelynn, Aten, Jan, Joles, Jaap A., Vial, Cecilia, Brandan, Enrique, Lyons, Karen M., Goldschmeding, Roel
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2008
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573007/
https://ncbi.nlm.nih.gov/pubmed/18632843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007111261
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