Effects of Antiproteinuric Intervention on Elevated Connective Tissue Growth Factor (CTGF/CCN-2) Plasma and Urine Levels in Nondiabetic Nephropathy

SUMMARY: BACKGROUND AND OBJECTIVES: Connective Tissue Growth Factor (CTGF/CCN-2) is a key player in fibrosis. Plasma CTGF levels predict end-stage renal disease and mortality in diabetic chronic kidney disease (CKD), supporting roles in intra- and extrarenal fibrosis. Few data are available on CTGF...

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Main Authors: Slagman, Maartje C.J., Nguyen, Tri Q., Waanders, Femke, Vogt, Liffert, Hemmelder, Marc H., Laverman, Gozewijn D., Goldschmeding, Roel, Navis, Gerjan
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2011
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359537/
https://ncbi.nlm.nih.gov/pubmed/21784839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.08190910
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