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The ribosomal protein gene RPL5 is a haploinsufficient tumor suppressor in multiple cancer types
For many years, defects in the ribosome have been associated to cancer. Recently, somatic mutations and deletions affecting ribosomal protein genes were identified in a few leukemias and solid tumor types. However, systematic analysis of all 81 known ribosomal protein genes across cancer types is la...
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| Veröffentlicht in: | Oncotarget |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5362418/ https://ncbi.nlm.nih.gov/pubmed/28147343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14895 |
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