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The ribosomal protein gene RPL5 is a haploinsufficient tumor suppressor in multiple cancer types

For many years, defects in the ribosome have been associated to cancer. Recently, somatic mutations and deletions affecting ribosomal protein genes were identified in a few leukemias and solid tumor types. However, systematic analysis of all 81 known ribosomal protein genes across cancer types is la...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Fancello, Laura, Kampen, Kim R., Hofman, Isabel J.F., Verbeeck, Jelle, Keersmaecker, Kim De
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362418/
https://ncbi.nlm.nih.gov/pubmed/28147343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14895
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