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The ribosomal protein gene RPL5 is a haploinsufficient tumor suppressor in multiple cancer types

For many years, defects in the ribosome have been associated to cancer. Recently, somatic mutations and deletions affecting ribosomal protein genes were identified in a few leukemias and solid tumor types. However, systematic analysis of all 81 known ribosomal protein genes across cancer types is la...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Fancello, Laura, Kampen, Kim R., Hofman, Isabel J.F., Verbeeck, Jelle, Keersmaecker, Kim De
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362418/
https://ncbi.nlm.nih.gov/pubmed/28147343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14895
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