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Ribosomal lesions promote oncogenic mutagenesis
Ribosomopathies are congenital disorders caused by mutations in ribosomal proteins (RP) or assembly factors and are characterized by cellular hypo-proliferation at an early stage. Paradoxically, many of these disorders have an elevated risk to progress to hyper-proliferative cancer at a later stage....
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| Publicado no: | Cancer Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7116100/ https://ncbi.nlm.nih.gov/pubmed/30482776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-1987 |
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