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The Ubiquitination, Disaggregation and Proteasomal Degradation Machineries in Polyglutamine Disease

Polyglutamine disorders are chronic, progressive neurodegenerative diseases caused by expansion of a glutamine tract in widely expressed genes. Despite excellent models of disease, a well-documented clinical history and progression, and established genetic causes, there are no FDA approved, disease...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Mol Neurosci
Egile Nagusiak: Nath, Samir R., Lieberman, Andrew P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360718/
https://ncbi.nlm.nih.gov/pubmed/28381987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00078
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