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Bisretinoid Degradation and the Ubiquitin-Proteasome System

Bisretinoid fluorophores of retinal pigment epithelial (RPE) lipofuscin have been shown to undergo degradation in two ways, the first involving photofragmentation following photooxidation of their polyene structure and the second being enzyme-mediated and limited, thus far, to in vitro models employ...

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Detalhes bibliográficos
Publicado no:Adv Exp Med Biol
Main Authors: Sparrow, Janet R., Zhou, Jilin, Ghosh, Shanti Kaligotla, Liu, Zhao
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832918/
https://ncbi.nlm.nih.gov/pubmed/24664748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4614-3209-8_75
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