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Complement Activation by Bisretinoid Constituents of RPE Lipofuscin

PURPOSE: Studies implicate activation of complement among the processes involved in the pathogenesis of age-related macular degeneration (AMD). Questions pertain to the trigger(s) responsible for the complement-associated events. The authors previously reported that photooxidation products of A2E ca...

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Autores principales: Zhou, Jilin, Kim, So Ra, Westlund, Barbro S., Sparrow, Janet R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669319/
https://ncbi.nlm.nih.gov/pubmed/19029031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2868
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