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PHOTOOXIDATION OF RPE LIPOFUSCIN BISRETINOIDS ENHANCES FLUORESCENCE INTENSITY*
Light-related cycling of chemically reactive vitamin A aldehyde leads to the formation autofluorescent bisretinoid pigments that accumulate as lipofuscin in retinal pigment epithelial cells. The amassing of these diretinoid compounds is implicated in the pathogenesis of age-related macular degenerat...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840058/ https://ncbi.nlm.nih.gov/pubmed/19800359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.visres.2009.09.015 |
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