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Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium
Recent studies have implicated local inflammation and activation of complement amongst the processes involved in the pathogenesis of age-related macular degeneration (AMD). Several lines of investigation also indicate that bis-retinoid pigments, such as A2E, that accumulate as lipofuscin in retinal...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1637557/ https://ncbi.nlm.nih.gov/pubmed/17060630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604255103 |
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