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Complement activation by photooxidation products of A2E, a lipofuscin constituent of the retinal pigment epithelium

Recent studies have implicated local inflammation and activation of complement amongst the processes involved in the pathogenesis of age-related macular degeneration (AMD). Several lines of investigation also indicate that bis-retinoid pigments, such as A2E, that accumulate as lipofuscin in retinal...

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書誌詳細
主要な著者: Zhou, Jilin, Jang, Young Pyo, Kim, So Ra, Sparrow, Janet R.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1637557/
https://ncbi.nlm.nih.gov/pubmed/17060630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604255103
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