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The all-trans-retinal dimer series of lipofuscin pigments in retinal pigment epithelial cells in a recessive Stargardt disease model

The bis-retinoid pigments that accumulate in retinal pigment epithelial cells as lipofuscin are associated with inherited and age-related retinal disease. In addition to A2E and related cis isomers, we previously showed that condensation of two molecules of all-trans-retinal leads to the formation o...

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Autores principales: Kim, So R., Jang, Young P., Jockusch, Steffen, Fishkin, Nathan E., Turro, Nicholas J., Sparrow, Janet R.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148280/
https://ncbi.nlm.nih.gov/pubmed/18048333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708714104
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