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Enzymatic Degradation of A2E, a Retinal Pigment Epithelial Lipofuscin Bisretinoid
[Image: see text] Some forms of blinding macular disease are associated with excessive accumulation of bisretinoid lipofuscin in retinal pigment epithelial (RPE) cells of the eye. This material is refractory to lysosomal enzyme degradation. In addition to gene and drug-based therapies, treatments th...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4112458/ https://ncbi.nlm.nih.gov/pubmed/21166406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja107195u |
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