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Enzymatic Degradation of A2E, a Retinal Pigment Epithelial Lipofuscin Bisretinoid

[Image: see text] Some forms of blinding macular disease are associated with excessive accumulation of bisretinoid lipofuscin in retinal pigment epithelial (RPE) cells of the eye. This material is refractory to lysosomal enzyme degradation. In addition to gene and drug-based therapies, treatments th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wu, Yalin, Zhou, Jilin, Fishkin, Nathan, Rittmann, Bruce E., Sparrow, Janet R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4112458/
https://ncbi.nlm.nih.gov/pubmed/21166406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja107195u
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