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Immunochemical recognition of A2E, a pigment in the lipofuscin of retinal pigment epithelial cells

The autofluorescent lipofuscin pigment A2E accumulates in retinal pigment epithelial cells with age and is particularly abundant in some retinal disorders. To generate a polyclonal antibody that recognizes this pyridinium bisretinoid molecule, we immunized rabbits with bovine serum albumin (BSA) con...

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Bibliografische gegevens
Hoofdauteurs: Abeywickrama, Chandima, Matsuda, Hiroko, Jockusch, Steffen, Zhou, Jilin, Jang, Young P., Chen, Bi-Xing, Itagaki, Yasuhiro, Erlanger, Bernard F., Nakanishi, Koji, Turro, Nicholas J., Sparrow, Janet R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976245/
https://ncbi.nlm.nih.gov/pubmed/17804788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706806104
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