Retinal Pigment Epithelium Lipofuscin Proteomics

Lipofuscin accumulates with age in the retinal pigment epithelium (RPE) in discrete granular organelles and may contribute to age-related macular degeneration. Because previous studies suggest that lipofuscin contains protein that may impact pathogenic mechanisms, we pursued proteomics analysis of l...

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Detalhes bibliográficos
Main Authors: Ng, Kwok-Peng, Gugiu, Bogdan, Renganathan, Kutralanathan, Davies, Matthew W., Gu, Xiaorong, Crabb, John S., Kim, So Ra, Różanowska, Malgorzata B., Bonilha, Vera L., Rayborn, Mary E., Salomon, Robert G., Sparrow, Janet R., Boulton, Michael E., Hollyfield, Joe G., Crabb, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493379/
https://ncbi.nlm.nih.gov/pubmed/18436525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M700525-MCP200
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