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DJ-1-Dependent Regulation of Oxidative Stress in the Retinal Pigment Epithelium (RPE)

BACKGROUND: DJ-1 is found in many tissues, including the brain, where it has been extensively studied due to its association with Parkinson’s disease. DJ-1 functions as a redox-sensitive molecular chaperone and transcription regulator that robustly protects cells from oxidative stress. METHODOLOGY:...

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Detalhes bibliográficos
Main Authors: Shadrach, Karen G., Rayborn, Mary E., Hollyfield, Joe G., Bonilha, Vera L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699467/
https://ncbi.nlm.nih.gov/pubmed/23844142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067983
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