Retinal Pigment Epithelium Lipofuscin Proteomics

Lipofuscin accumulates with age in the retinal pigment epithelium (RPE) in discrete granular organelles and may contribute to age-related macular degeneration. Because previous studies suggest that lipofuscin contains protein that may impact pathogenic mechanisms, we pursued proteomics analysis of l...

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Bibliographic Details
Main Authors: Ng, Kwok-Peng, Gugiu, Bogdan, Renganathan, Kutralanathan, Davies, Matthew W., Gu, Xiaorong, Crabb, John S., Kim, So Ra, Różanowska, Malgorzata B., Bonilha, Vera L., Rayborn, Mary E., Salomon, Robert G., Sparrow, Janet R., Boulton, Michael E., Hollyfield, Joe G., Crabb, John W.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493379/
https://ncbi.nlm.nih.gov/pubmed/18436525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M700525-MCP200
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