Retinal Pigment Epithelium Lipofuscin Proteomics

Lipofuscin accumulates with age in the retinal pigment epithelium (RPE) in discrete granular organelles and may contribute to age-related macular degeneration. Because previous studies suggest that lipofuscin contains protein that may impact pathogenic mechanisms, we pursued proteomics analysis of l...

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Autori principali: Ng, Kwok-Peng, Gugiu, Bogdan, Renganathan, Kutralanathan, Davies, Matthew W., Gu, Xiaorong, Crabb, John S., Kim, So Ra, Różanowska, Malgorzata B., Bonilha, Vera L., Rayborn, Mary E., Salomon, Robert G., Sparrow, Janet R., Boulton, Michael E., Hollyfield, Joe G., Crabb, John W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493379/
https://ncbi.nlm.nih.gov/pubmed/18436525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M700525-MCP200
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