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Intranuclear Degradation of Polyglutamine Aggregates by the Ubiquitin-Proteasome System
Huntington disease and its related autosomal-dominant polyglutamine (pQ) neurodegenerative diseases are characterized by intraneuronal accumulation of protein aggregates. Studies on protein aggregates have revealed the importance of the ubiquitin-proteasome system as the front line of protein qualit...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665101/ https://ncbi.nlm.nih.gov/pubmed/19218238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809739200 |
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