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FAT10 Protein Binds to Polyglutamine Proteins and Modulates Their Solubility
Expansion of polyglutamine (pQ) chain by expanded CAG repeat causes dominantly inherited neurodegeneration such as Huntington disease, dentatorubral-pallidoluysian atrophy (DRPLA), and numbers of other spinocerebellar ataxias. Expanded pQ disrupts the stability of the pQ-harboring protein and increa...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3191000/ https://ncbi.nlm.nih.gov/pubmed/21757738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.261032 |
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