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Drug-Induced Liver Injury: Advances in Mechanistic Understanding that will Inform Risk Management

Drug-induced liver injury (DILI) is a major public health problem. Intrinsic (dose-dependent) DILI associated with acetaminophen overdose is the number one cause of acute liver failure in the US. However the most problematic type of DILI impacting drug development is idiosyncratic, occurring only ve...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Pharmacol Ther
Prif Awduron: Mosedale, Merrie, Watkins, Paul B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359062/
https://ncbi.nlm.nih.gov/pubmed/27861792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.564
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