Mechanistic Modelling of Drug-Induced Liver Injury: Investigating the Role of Innate Immune Responses

Drug-induced liver injury (DILI) remains an adverse event of significant concern for drug development and marketed drugs, and the field would benefit from better tools to identify liver liabilities early in development and/or to mitigate potential DILI risk in otherwise promising drugs. DILIsym soft...

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Enregistré dans:
Détails bibliographiques
Publié dans:Gene Regul Syst Bio
Auteurs principaux: Shoda, Lisl KM, Battista, Christina, Siler, Scott Q, Pisetsky, David S, Watkins, Paul B, Howell, Brett A
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2017
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459514/
https://ncbi.nlm.nih.gov/pubmed/28615926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1177625017696074
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