Mechanistic Modelling of Drug-Induced Liver Injury: Investigating the Role of Innate Immune Responses

Drug-induced liver injury (DILI) remains an adverse event of significant concern for drug development and marketed drugs, and the field would benefit from better tools to identify liver liabilities early in development and/or to mitigate potential DILI risk in otherwise promising drugs. DILIsym soft...

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Bibliografiske detaljer
Udgivet i:Gene Regul Syst Bio
Main Authors: Shoda, Lisl KM, Battista, Christina, Siler, Scott Q, Pisetsky, David S, Watkins, Paul B, Howell, Brett A
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459514/
https://ncbi.nlm.nih.gov/pubmed/28615926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1177625017696074
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