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Drug-Induced Liver Injury: Advances in Mechanistic Understanding that will Inform Risk Management
Drug-induced liver injury (DILI) is a major public health problem. Intrinsic (dose-dependent) DILI associated with acetaminophen overdose is the number one cause of acute liver failure in the US. However the most problematic type of DILI impacting drug development is idiosyncratic, occurring only ve...
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| Veröffentlicht in: | Clin Pharmacol Ther |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5359062/ https://ncbi.nlm.nih.gov/pubmed/27861792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.564 |
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