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Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals
Nuclear export receptor CRM1 binds highly variable nuclear export signals (NESs) in hundreds of different cargoes. Previously we have shown that CRM1 binds NESs in both polypeptide orientations (Fung et al., 2015). Here, we show crystal structures of CRM1 bound to eight additional NESs which reveal...
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| Publicado no: | eLife |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5358978/ https://ncbi.nlm.nih.gov/pubmed/28282025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23961 |
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