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Structural basis for assembly and disassembly of the CRM1 nuclear export complex
CRM1 (or exportin 1, Xpo1) transports proteins out of the cell nucleus through the nuclear pore complex. In the cytoplasm, GTP hydrolysis and consequent dissociation of Ran from CRM1 releases low-affinity substrates, while additional factors facilitate release of high-affinity substrates. Here we pr...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3437629/ https://ncbi.nlm.nih.gov/pubmed/19339972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1586 |
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