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Mechanistic insights from the recent structures of the CRM1 nuclear export complex and its disassembly intermediate

CRM1 (also known as exportin 1 or Xpo1) is the most versatile nuclear export receptor (exportin) that carries a broad range of proteins and ribonucleoproteins from the nucleus to the cytoplasm through the nuclear pore complex. The majority of the export substrates of CRM1 contain a short peptide seq...

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Détails bibliographiques
Publié dans:Biophysics (Nagoya-shi)
Auteurs principaux: Koyama, Masako, Matsuura, Yoshiyuki
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society of Japan (BSJ) 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629651/
https://ncbi.nlm.nih.gov/pubmed/27493531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2142/biophysics.8.145
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