Rps3/uS3 promotes mRNA binding at the 40S ribosome entry channel and stabilizes preinitiation complexes at start codons

The eukaryotic 43S preinitiation complex (PIC) bearing Met-tRNA(i)(Met) in a ternary complex (TC) with eukaryotic initiation factor (eIF)2-GTP scans the mRNA leader for an AUG codon in favorable “Kozak” context. AUG recognition provokes rearrangement from an open PIC conformation with TC bound in a...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Dong, Jinsheng, Aitken, Colin Echeverría, Thakur, Anil, Shin, Byung-Sik, Lorsch, Jon R., Hinnebusch, Alan G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358355/
https://ncbi.nlm.nih.gov/pubmed/28223523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620569114
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker