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Conserved residues in yeast initiator tRNA calibrate initiation accuracy by regulating preinitiation complex stability at the start codon
Eukaryotic initiator tRNA (tRNA(i)) contains several highly conserved unique sequence features, but their importance in accurate start codon selection was unknown. Here we show that conserved bases throughout tRNA(i), from the anticodon stem to acceptor stem, play key roles in ensuring the fidelity...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3950347/ https://ncbi.nlm.nih.gov/pubmed/24589778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.236547.113 |
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