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11-Step Enantioselective Synthesis of (−)-Lomaiviticin Aglycon
Lomaiviticins A and B are complex antitumor antibiotics that were isolated from a strain of Micromonospora. A confluence of several unusual structural features renders the lomaiviticins exceedingly challenging targets for chemical synthesis. We report an 11-step, enantioselective synthetic route to...
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| Published in: | J Am Chem Soc |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5357143/ https://ncbi.nlm.nih.gov/pubmed/21280607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja200034b |
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