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Thrombin inhibition and cisplatin block tumor progression in ovarian cancer by alleviating the immunosuppressive microenvironment

Cancer is often associated with an increased risk of thrombotic complications which can be aggravated by treatment with chemotherapeutics such as cisplatin. Multiple lines of evidence suggest that thrombin activity promotes tumor growth and metastasis. We examined the effect of co-treatment with dab...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Alexander, Eric T., Minton, Allyson R., Peters, Molly C., van Ryn, Joanne, Gilmour, Susan K.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356737/
https://ncbi.nlm.nih.gov/pubmed/27852034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13300
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