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Thrombin inhibition and cisplatin block tumor progression in ovarian cancer by alleviating the immunosuppressive microenvironment

Cancer is often associated with an increased risk of thrombotic complications which can be aggravated by treatment with chemotherapeutics such as cisplatin. Multiple lines of evidence suggest that thrombin activity promotes tumor growth and metastasis. We examined the effect of co-treatment with dab...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Alexander, Eric T., Minton, Allyson R., Peters, Molly C., van Ryn, Joanne, Gilmour, Susan K.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356737/
https://ncbi.nlm.nih.gov/pubmed/27852034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13300
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