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A novel polyamine blockade therapy activates an anti-tumor immune response
Most tumors maintain elevated levels of polyamines to support their growth and survival. This study explores the anti-tumor effect of polyamine starvation via both inhibiting polyamine biosynthesis and blocking the upregulated import of polyamines into the tumor. We demonstrate that polyamine blocka...
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| Publié dans: | Oncotarget |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Impact Journals LLC
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5663583/ https://ncbi.nlm.nih.gov/pubmed/29137411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20493 |
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