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Thrombin inhibition and cyclophosphamide synergistically block tumor progression and metastasis
Cancer is often associated with an increased risk of thrombotic events which are exacerbated by treatment with chemotherapeutics such as cyclosphosphamide (CP). Evidence suggests that thrombin can stimulate tumor progression via formation of fibrin and activation of protease-activated receptors (PAR...
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| Publié dans: | Cancer Biol Ther |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4847815/ https://ncbi.nlm.nih.gov/pubmed/26383051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1078025 |
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