Thrombin inhibition and cyclophosphamide synergistically block tumor progression and metastasis

Cancer is often associated with an increased risk of thrombotic events which are exacerbated by treatment with chemotherapeutics such as cyclosphosphamide (CP). Evidence suggests that thrombin can stimulate tumor progression via formation of fibrin and activation of protease-activated receptors (PAR...

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Detaylı Bibliyografya
Yayımlandı:Cancer Biol Ther
Asıl Yazarlar: Alexander, Eric T, Minton, Allyson R, Hayes, Candace S, Goss, Ashley, Van Ryn, Joanne, Gilmour, Susan K
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2015
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847815/
https://ncbi.nlm.nih.gov/pubmed/26383051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1078025
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