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Thrombin inhibition and cyclophosphamide synergistically block tumor progression and metastasis

Cancer is often associated with an increased risk of thrombotic events which are exacerbated by treatment with chemotherapeutics such as cyclosphosphamide (CP). Evidence suggests that thrombin can stimulate tumor progression via formation of fibrin and activation of protease-activated receptors (PAR...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cancer Biol Ther
Päätekijät: Alexander, Eric T, Minton, Allyson R, Hayes, Candace S, Goss, Ashley, Van Ryn, Joanne, Gilmour, Susan K
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847815/
https://ncbi.nlm.nih.gov/pubmed/26383051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1078025
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