Synergistic Protection in Lung Ischemia-Reperfusion Injury With Calcineurin and Thrombin Inhibition

BACKGROUND: Ischemia-reperfusion injury impairs lung transplant outcomes. The transcription factors, activator protein-1, and nuclear factor kappa B, are activated early in reperfusion and drive the development of injury. Thrombin inhibition with hirudin, and calcineurin inhibition with tacrolimus h...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: McCourtie, Anton S., Merry, Heather E., Wolf, Patrick S., FitzSullivan, Elizabeth, Keech, John C., Farivar, Alexander S., Mulligan, Michael S.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052279/
https://ncbi.nlm.nih.gov/pubmed/20494024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2010.02.068
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires