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VALIDATING THE USE OF SIRNA AS A NOVEL TECHNIQUE FOR CELL SPECIFIC TARGET GENE KNOCKDOWN IN LUNG ISCHEMIA-REPERFUSION INJURY

OBJECTIVE: Short interfering RNA is an effective method for target gene knockdown. However, concerns surround their design, administration, efficacy, specificity and immunostimulatory potential. Though uptake by alveolar macrophages has been demonstrated, studies have not examined its use in lung is...

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Bibliografiske detaljer
Udgivet i:J Thorac Cardiovasc Surg
Main Authors: Merry, Heather E., Phelan, Patrick, Hwang, Billanna, Mulligan, Michael S.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727997/
https://ncbi.nlm.nih.gov/pubmed/26687890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2015.09.125
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