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VALIDATING THE USE OF SIRNA AS A NOVEL TECHNIQUE FOR CELL SPECIFIC TARGET GENE KNOCKDOWN IN LUNG ISCHEMIA-REPERFUSION INJURY

OBJECTIVE: Short interfering RNA is an effective method for target gene knockdown. However, concerns surround their design, administration, efficacy, specificity and immunostimulatory potential. Though uptake by alveolar macrophages has been demonstrated, studies have not examined its use in lung is...

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Detalhes bibliográficos
Publicado no:J Thorac Cardiovasc Surg
Main Authors: Merry, Heather E., Phelan, Patrick, Hwang, Billanna, Mulligan, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727997/
https://ncbi.nlm.nih.gov/pubmed/26687890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2015.09.125
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