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VALIDATING THE USE OF SIRNA AS A NOVEL TECHNIQUE FOR CELL SPECIFIC TARGET GENE KNOCKDOWN IN LUNG ISCHEMIA-REPERFUSION INJURY

OBJECTIVE: Short interfering RNA is an effective method for target gene knockdown. However, concerns surround their design, administration, efficacy, specificity and immunostimulatory potential. Though uptake by alveolar macrophages has been demonstrated, studies have not examined its use in lung is...

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Detalles Bibliográficos
Publicado en:J Thorac Cardiovasc Surg
Autores principales: Merry, Heather E., Phelan, Patrick, Hwang, Billanna, Mulligan, Michael S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727997/
https://ncbi.nlm.nih.gov/pubmed/26687890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2015.09.125
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