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Proteolytic properties of single-chain factor XII: a mechanism for triggering contact activation

When blood is exposed to variety of artificial surfaces and biologic substances, the plasma proteins factor XII (FXII) and prekallikrein undergo reciprocal proteolytic conversion to the proteases αFXIIa and α-kallikrein by a process called contact activation. These enzymes contribute to host-defense...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Blood
Päätekijät: Ivanov, Ivan, Matafonov, Anton, Sun, Mao-fu, Cheng, Qiufang, Dickeson, S. Kent, Verhamme, Ingrid M., Emsley, Jonas, Gailani, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356457/
https://ncbi.nlm.nih.gov/pubmed/28069606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-10-744110
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