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Single-Chain Factor XII – A New Form of Activated Factor XII
PURPOSE: Exposure of blood to foreign surfaces induces reciprocal conversion of the plasma proteins factor XII (fXII) and plasma prekallikrein (PPK) to the proteases α-fXIIa and α-kallikrein. This process, called contact activation, has a range of effects on host defense mechanisms, including promot...
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| Gepubliceerd in: | Curr Opin Hematol |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5762122/ https://ncbi.nlm.nih.gov/pubmed/28604413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MOH.0000000000000363 |
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